Effects of polybrominated diphenyl ethers on steroidogenesis in rat Leydig cells

Effects of polybrominated diphenyl ethers on steroidogenesis in rat Leydig cells.

BACKGROUND Polybrominated diphenyl ethers (PBDEs) are brominated flame retardants that have been defined as major environmental pollutants. While previous studies have found that PBDEs may enhance the levels of sex-steroid hormones, their effects on testosterone secretion from rat Leydig cells are unclear. This study investigated the effects and mechanisms of PBDE-710, a mixture of tetra- and p...

Polybrominated Diphenyl Ethers in the Canadian Environment

Polybrominated diphenyl ethers in UK human milk

24 Fourteen tri-deca polybrominated diphenyl ethers (PBDEs) were investigated in 35 human 25 milk samples from Birmingham, UK. While none of the hepta-nona BDEs (the main 26 components of the OctaBDE technical mixture) were above the limit of quantitation (LOQ); 27 BDE-47 (average concentration = 3.3 ng g lipid weight (lw)) was quantified in all samples 28 contributing 34-74% to Σtri-hexa BDEs ...

Polybrominated diphenyl ethers and polybrominated biphenyls in Australian sewage sludge.

This paper presents a brief review of the international scientific literature of polybrominated diphenyl ethers (PBDEs) and polybrominated biphenyls (PBBs) in sewage sludge and a survey of these compounds in sewage sludge from 16 Australian wastewater treatment plants (WWTPs). The SigmaPBDE mean concentration in the Australian study was 1137microgkg(-1) dry weight (d.w.) (s.d. 1116) and ranged ...

A Theoretical Study on Reductive Debromination of Polybrominated Diphenyl Ethers

Recent progress has been made in the reductive debromination of polybrominated diphenyl ethers (PBDEs) by nanoscale zero-valent iron (nZVI). To better understand the mechanism of this reaction, seven selected BDE congeners and their anions were investigated at the density functional theory (DFT) level using four different methods, including B3LYP/6-31G(d), B3LYP/6-31+G(d), B3LYP/6-31G(d,p) and ...